Fecal Microbiome and Bile Acid Profiles Differ in Preterm Infants with Parenteral Nutrition-associated Cholestasis
This is the first study to directly explore the relationship between PNAC susceptibility, the microbiome, and fecal bile acids in preterm infants. The microbiome and bile acid patterns identified here may inform the development of targeted therapeutics for this vulnerable population.
Authors
- Erika C. Claud (ORCID: https://orcid.org/0000-0002-2408-2114)
- Kaitlyn Oliphant (ORCID: https://orcid.org/0000-0002-6921-7094)
- Ruba Azzam
- Bree Andrews
- Mark D’Souza
- Ellen Wagner
- Wilfredo Cruz-Ayala
Institutions
- University of Chicago (US)
Publication Details
- Journal
- Journal of Clinical and Translational Hepatology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.14218/jcth.2025.00152
- Primary Topic
- Infant Nutrition and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health