Endocannabinoid response to social stress in chronic non-medical prescription opioid users
Results suggest dysfunctional stress response at the level of the ECS in individuals with NMPOU. Specifically 2-AG might play a critical role in stress resilience and, thus, it might be a potential pharmacotherapeutic target in the treatment of OUD.
Authors
- Jürg Gertsch (ORCID: https://orcid.org/0000-0003-0978-1555)
- Daniele Pellegata (ORCID: https://orcid.org/0000-0001-9666-7560)
- Boris B. Quednow (ORCID: https://orcid.org/0000-0001-7933-2865)
- Philip Meier (ORCID: https://orcid.org/0000-0001-7789-7002)
- Sara L. Kroll (ORCID: https://orcid.org/0000-0001-9823-5171)
- Volkmar H.R. Schmid
Institutions
- University of Bern (CH)
- University of Zurich (CH)
- University Hospital of Zurich (CH)
Publication Details
- Journal
- Psychopharmacology
- Published
- 2025-11-05
- DOI
- https://doi.org/10.1007/s00213-025-06950-4
- Citations
- 1
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Science Foundation
- National Alliance for Research on Schizophrenia and Depression
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Universität Zürich
- Uniscientia Foundation