A Rare Case of Right Testicular Leiomyosarcoma With Hepatic and Pulmonary Metastases

Testicular leiomyosarcoma is an exceptionally rare malignant mesenchymal tumour with limited documentation in the literature. We report the case of a 50-year-old male presenting with progressive scrotal swelling and pain, who was diagnosed with right testicular leiomyosarcoma with synchronous hepatic and pulmonary metastases. The patient underwent right high orchiectomy, followed by systemic chemotherapy. Disease progression occurred after anthracycline-ifosfamide, requiring second-line docetaxel. This case highlights the aggressive clinical course and therapeutic challenges of testicular leiomyosarcoma, underscoring the need for more cumulative evidence to guide management.

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Journal
Cureus
Published
2025-11-04
DOI
https://doi.org/10.7759/cureus.96099
Primary Topic
Testicular diseases and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

A Rare Case of Right Testicular Leiomyosarcoma With Hepatic and Pulmonary Metastases

Ashwin Ravichandran, Kavi Chakravarthi M G, Kavuru Naga Siri, Bhargav Vuppumalla et al.
Cureus
Testicular diseases and treatments
article

A Rare Case of Right Testicular Leiomyosarcoma With Hepatic and Pulmonary Metastases

Ashwin Ravichandran, Kavi Chakravarthi M G, Kavuru Naga Siri, Bhargav Vuppumalla, Yatish M Ellini
article en

Abstract

Testicular leiomyosarcoma is an exceptionally rare malignant mesenchymal tumour with limited documentation in the literature. We report the case of a 50-year-old male presenting with progressive scrotal swelling and pain, who was diagnosed with right testicular leiomyosarcoma with synchronous hepatic and pulmonary metastases. The patient underwent right high orchiectomy, followed by systemic chemotherapy. Disease progression occurred after anthracycline-ifosfamide, requiring second-line docetaxel. This case highlights the aggressive clinical course and therapeutic challenges of testicular leiomyosarcoma, underscoring the need for more cumulative evidence to guide management.

CureusVol. 17(11)
Shri Venkateshwara University (IN), Sri Ramachandra Institute of Higher Education and Research (IN), Sri Venkateshwaraa Medical College Hospital and Research Centre (IN)
Openalex Percentile: Top 49%
Testicular diseases and treatments
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