Visualization of Topical Roflumilast Versus Vehicle using Line-Field Optical Coherence Tomography in Healthy Skin

LC-OCT visualized roflumilast's effects on healthy skin, including reduced hyperreflective material consistent with mottled pigmentation and normalized keratinocyte organization, suggesting the effects it has on healthy skin. The AI algorithm showed lasting effects on SC thickness, even after discontinuation of treatment.

Authors

Publication Details

Journal
Journal of Drugs in Dermatology
Published
2025-10-01
DOI
https://doi.org/10.36849/jdd.08735
Primary Topic
Optical Coherence Tomography Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Visualization of Topical Roflumilast Versus Vehicle using Line-Field Optical Coherence Tomography in Healthy Skin

Babar Rao, Madeline Tchack, Noah Musolff, Bassem Rafiq
Journal of Drugs in Dermatology
Optical Coherence Tomography Applications
article

Visualization of Topical Roflumilast Versus Vehicle using Line-Field Optical Coherence Tomography in Healthy Skin

Babar Rao, Madeline Tchack, Noah Musolff, Bassem Rafiq
article en

Abstract

LC-OCT visualized roflumilast's effects on healthy skin, including reduced hyperreflective material consistent with mottled pigmentation and normalized keratinocyte organization, suggesting the effects it has on healthy skin. The AI algorithm showed lasting effects on SC thickness, even after discontinuation of treatment.

Journal of Drugs in DermatologyVol. 24(11)
Openalex Percentile: Top 68%
Optical Coherence Tomography Applications
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Visualization of Topical Roflumilast Versus Vehicle using Line-Field Optical Coherence Tomography in Healthy Skin — Babar Rao, Madeline Tchack, et al. · Journal of Drugs in Dermatology (2025) | TGRS Research Map | TGRS