Exploration of adverse event profiles for glofitamab: A disproportionality analysis using the FDA adverse event reporting system

The findings suggest potential reporting differences in glofitamab-related AEs across different continents. Educating consumers on how to recognize the early symptoms of cytokine release syndrome is essential to improve safety. Close monitoring of cytokine release syndrome is recommended within 30 days of administration of glofitamab, especially at a dose of 2.5 mg. Furthermore, it is essential to stay vigilant about the emergence of the newly identified AE. These findings contribute to a broader understanding of the AE profiles of glofitamab.

Authors

Institutions

Publication Details

Journal
PLoS ONE
Published
2025-11-04
DOI
https://doi.org/10.1371/journal.pone.0336151
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Exploration of adverse event profiles for glofitamab: A disproportionality analysis using the FDA adverse event reporting system

Cheng Jiang, Chuanyong Su, Meng Zhou
PLoS ONE
Drug-Induced Adverse Reactions
article

Exploration of adverse event profiles for glofitamab: A disproportionality analysis using the FDA adverse event reporting system

Cheng Jiang, Chuanyong Su, Meng Zhou
article en

Abstract

The findings suggest potential reporting differences in glofitamab-related AEs across different continents. Educating consumers on how to recognize the early symptoms of cytokine release syndrome is essential to improve safety. Close monitoring of cytokine release syndrome is recommended within 30 days of administration of glofitamab, especially at a dose of 2.5 mg. Furthermore, it is essential to stay vigilant about the emergence of the newly identified AE. These findings contribute to a broader understanding of the AE profiles of glofitamab.

PLoS ONEVol. 20(11)
Zhejiang Chinese Medical University (CN), Zhejiang Provincial Hospital of TCM (CN), Tongde Hospital of Zhejiang Province (CN), Zhejiang Cancer Hospital (CN), Hangzhou Hospital of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 64%
Drug-Induced Adverse Reactions
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.