Exploration of adverse event profiles for glofitamab: A disproportionality analysis using the FDA adverse event reporting system
The findings suggest potential reporting differences in glofitamab-related AEs across different continents. Educating consumers on how to recognize the early symptoms of cytokine release syndrome is essential to improve safety. Close monitoring of cytokine release syndrome is recommended within 30 days of administration of glofitamab, especially at a dose of 2.5 mg. Furthermore, it is essential to stay vigilant about the emergence of the newly identified AE. These findings contribute to a broader understanding of the AE profiles of glofitamab.
Authors
- Cheng Jiang (ORCID: https://orcid.org/0000-0001-8454-749X)
- Chuanyong Su (ORCID: https://orcid.org/0000-0002-6984-2666)
- Meng Zhou (ORCID: https://orcid.org/0000-0001-8598-5643)
Institutions
- Zhejiang Chinese Medical University (CN)
- Zhejiang Provincial Hospital of TCM (CN)
- Tongde Hospital of Zhejiang Province (CN)
- Zhejiang Cancer Hospital (CN)
- Hangzhou Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1371/journal.pone.0336151
- Primary Topic
- Drug-Induced Adverse Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00