Nanoliposomal Irinotecan With Fluorouracil and Folinic Acid in Older Versus Younger Patients With Unresectable Pancreatic Cancer: The Multicenter NAPOLEON‐2 Study
Older patients with pancreatic cancer may benefit from NFF to the same extent as younger patients without severe adverse events. GNRI needs further study as a predictor of NFF efficacy in older patients.
Authors
- Shigeyuki Takeshita
- Kengo Tsuneyoshi
- Hiroki Taguchi
- Mototsugu Shimokawa (ORCID: https://orcid.org/0000-0001-8140-4565)
- Taro Shibuki (ORCID: https://orcid.org/0000-0001-7302-7691)
- Junichi Nakazawa
- Keisuke Miwa (ORCID: https://orcid.org/0000-0002-2456-0358)
- Toshihiko Mizuta
- Takahiro Sakae
- Hozumi Shimokawa
- Kazuo Nishikawa (ORCID: https://orcid.org/0000-0003-1397-953X)
- Yoshihito Kubotsu
- Yujiro Ueda (ORCID: https://orcid.org/0000-0001-8340-0023)
- Takuya Honda (ORCID: https://orcid.org/0000-0002-7141-0088)
- Shuji Arita
- Tsuyoshi Shirakawa (ORCID: https://orcid.org/0000-0002-9317-8216)
- Atsuko Kakihara
- Toshihiro Fujita
- Kenji Mitsugi
- Ayumu Hosokawa (ORCID: https://orcid.org/0009-0003-6913-6950)
- Yasunori Kawaguchi
- Taiga Otsuka (ORCID: https://orcid.org/0000-0002-8552-8095)
- Azusa Komori (ORCID: https://orcid.org/0000-0003-0591-1025)
- Hisanobu Oda
- Tatsunori Sakai
- Akio Ido
- Satoshi Otsu
- Futa Koga
- Shiho Arima
- Machiko Kawahira
Institutions
- Kagoshima University (JP)
- University of Nagasaki (JP)
- Yamaguchi University (JP)
- Oita University (JP)
- Japanese Red Cross Society, Japan (JP)
- Fukuoka University (JP)
- Japan Hospital Association (JP)
- Sasebo City General Hospital (JP)
- National Hospital Organization Kyushu Cancer Center (JP)
- Takamatsu Red Cross Hospital (JP)
- Kurume University Hospital (JP)
- Fukuoka Hospital (JP)
- Saiseikai Kumamoto Hospital (JP)
- Saga-Ken Medical Centre Koseikan (JP)
- Japanese Red Cross Kumamoto Hospital (JP)
- Miyazaki Prefectural Hospital (JP)
- Kyushu Hospital (JP)
- Kagoshima University Hospital (JP)
- Kagoshima City Hospital (JP)
- Nishikawa Hospital (JP)
- Ono Clinic (JP)
- Izumi City General Hospital (JP)
- Japan Community Healthcare Organization (JP)
- University of Miyazaki Hospital (JP)
- Shikoku Cancer Center (JP)
- Kagoshima Medical Center (JP)
- National Cancer Center Hospital East (JP)
- Saiseikai Shigaken Hospital (JP)
- Sendai Shakai Hoken Hospital (JP)
- Nagasaki University Hospital (JP)
- Kumamoto Medical Center (JP)
- Nagasaki University (JP)
Publication Details
- Journal
- Asia-Pacific Journal of Clinical Oncology
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1111/ajco.70041
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00