Molecular and epidemiology characterization of carbapenem-resistant Escherichia coli in Hangzhou, China
This was a survey on the prevalence and molecular characteristics of CR-EC in Hangzhou. blaNDM-like production combined with extended spectrum beta-lactamase (ESBLs) and/or AmpC was the main resistance mechanism of CR-EC in this area. The dominant blaNDM-5-ST410 requires enhanced attention. The horizontal transformation of plasmids, complex drug resistance, and potential virulence risks also need close attention.
Authors
- Shaoshan Liu (ORCID: https://orcid.org/0000-0002-2673-5545)
- Kewang Hu
- Lingyi Zeng (ORCID: https://orcid.org/0009-0001-3710-2129)
- Jun Li (ORCID: https://orcid.org/0000-0001-7218-429X)
- Wei Zheng (ORCID: https://orcid.org/0009-0001-6615-0728)
- Zhibei Zheng
- Qihao Xu
- Jiaqi Yan (ORCID: https://orcid.org/0000-0002-6540-698X)
- Hua Yu (ORCID: https://orcid.org/0000-0002-6896-8056)
- Mengdie Xiang
Institutions
- Zhejiang Chinese Medical University (CN)
- Hangzhou Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- The Journal of Infection in Developing Countries
- Published
- 2025-10-31
- DOI
- https://doi.org/10.3855/jidc.20759
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00