A Validation Study of an Expanded Description of Glandular (Acinar)/Tubule Formation for the Use of Nottingham Grading System for Invasive Breast Carcinomas Demonstrates Improvement in Concordance for Breast Pathologists and Trainees in Pathology
The expanded description assisted in the recognition of G/TF for both breast pathologists and trainees. The most important impact on grading will likely be for carcinomas with complex cribriform patterns or micropapillary patterns with "inverted tubules." Participants endorsed that the expanded description of G/TF and the annotated images would be helpful reference material for pathologists.
Authors
- Stuart J. Schnitt (ORCID: https://orcid.org/0000-0002-3608-7828)
- Cansu Karakaş (ORCID: https://orcid.org/0000-0003-0357-5224)
- Susan C. Lester (ORCID: https://orcid.org/0000-0002-6345-1664)
- Ian O. Ellis
- Marie-Hélène Ngo (ORCID: https://orcid.org/0000-0001-5666-1308)
- Rana Aldrees
- Susan Fineberg (ORCID: https://orcid.org/0000-0002-4769-7875)
- Anas Mohamed (ORCID: https://orcid.org/0000-0003-0807-5616)
Institutions
- Brigham and Women's Hospital (US)
- Albert Einstein College of Medicine (US)
- University of Nottingham (GB)
- Nottingham City Hospital (GB)
- Hôpital Maisonneuve-Rosemont (CA)
- Stanford Medicine (US)
- Mass General Brigham (US)
- Stanford University (US)
Publication Details
- Journal
- Archives of Pathology & Laboratory Medicine
- Published
- 2025-11-03
- DOI
- https://doi.org/10.5858/arpa.2025-0280-oa
- Primary Topic
- Breast Lesions and Carcinomas
- Type
- article
- Field-Weighted Citation Impact
- 0.00