DTI changes of brachial plexus nerve roots in amyotrophic lateral sclerosis and their correlation with electrophysiology

Lower Fractional anisotropy (FA) and axial diffusivity (AD), and higher radial diffusivity (RD) were shown in amyotrophic lateral sclerosis (ALS) brachial plexus. Diffusion tensor imaging (DTI) parameters correlated with clinical and electrophysiological parameters. FA, AD, and RD detected ALS nerve microstructural changes, indicating abnormal conduction function.

Authors

Man Xiao (ORCID: https://orcid.org/0000-0001-9025-3228)
Guangbin Wang (ORCID: https://orcid.org/0000-0001-7410-5540)
Yuxin Li (ORCID: https://orcid.org/0000-0001-7404-6595)
Shanshan Wang
Yufan Chen (ORCID: https://orcid.org/0000-0002-3501-9807)
Xin Xing (ORCID: https://orcid.org/0000-0001-6417-0664)

Institutions

Shandong Provincial Hospital (CN)
Shandong First Medical University (CN)

Publication Details

Journal: European Radiology Experimental
Published: 2025-11-04
DOI: https://doi.org/10.1186/s41747-025-00645-3
Primary Topic: Amyotrophic Lateral Sclerosis Research
Type: article
Field-Weighted Citation Impact: 0.00

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article

DTI changes of brachial plexus nerve roots in amyotrophic lateral sclerosis and their correlation with electrophysiology

Man Xiao, Guangbin Wang, Yuxin Li, Shanshan Wang et al.

Nov 4, 2025

European Radiology Experimental

Amyotrophic Lateral Sclerosis Research

article

DTI changes of brachial plexus nerve roots in amyotrophic lateral sclerosis and their correlation with electrophysiology

Man Xiao, Guangbin Wang, Yuxin Li, Shanshan Wang, Yufan Chen, Xin Xing

November 4, 2025article en

Abstract

Lower Fractional anisotropy (FA) and axial diffusivity (AD), and higher radial diffusivity (RD) were shown in amyotrophic lateral sclerosis (ALS) brachial plexus. Diffusion tensor imaging (DTI) parameters correlated with clinical and electrophysiological parameters. FA, AD, and RD detected ALS nerve microstructural changes, indicating abnormal conduction function.

European Radiology ExperimentalVol. 9(1)

Shandong Provincial Hospital (CN), Shandong First Medical University (CN)

Openalex Percentile: Top 54%

Amyotrophic Lateral Sclerosis Research

DOI Open Access PDF OpenAlex

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DTI changes of brachial plexus nerve roots in amyotrophic lateral sclerosis and their correlation with electrophysiology — Man Xiao, Guangbin Wang, et al. · European Radiology Experimental (2025) | TGRS Research Map | TGRS