R-loop accumulation promotes OSCC malignant progression by upregulating MARVELD3 expression
In conclusion, R-loop accumulation promotes transcription of the MARVELD3. MARVELD3 exerts a tumor-promoting effect in OSCC by downregulating TTC9 and activating the MAPK signaling pathway.
Authors
- Xinyi Li (ORCID: https://orcid.org/0000-0003-4126-2894)
- Tingxiu Xiang (ORCID: https://orcid.org/0000-0003-4589-0599)
- Xuerong Xiang
- Jiao Huang (ORCID: https://orcid.org/0000-0002-1234-499X)
- Ping Ji (ORCID: https://orcid.org/0000-0003-2271-2335)
Institutions
- Stomatological Hospital of Chongqing Medical University (CN)
- Chongqing Cancer Hospital (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Bioorganic Chemistry
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1016/j.bioorg.2025.109180
- Citations
- 1
- Primary Topic
- DNA Repair Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.81