Traumatic Spinal Cord Injury and Subsequent Risk of Developing Chronic Cardiovascular, Neurologic, Psychiatric, and Endocrine Disorders
In this cohort study, TSCI was associated with increased long-term risk of multisystem morbidity and elevated mortality-even in previously healthy patients. These findings underscore the need for proactive, longitudinal, and multidisciplinary approaches to prevent complications and protect this high-risk population.
Authors
- Joshua D. Bernstock (ORCID: https://orcid.org/0000-0002-7814-3867)
- Ross Zafonte (ORCID: https://orcid.org/0000-0002-1050-796X)
- Maryam H. Al Mansi (ORCID: https://orcid.org/0000-0003-4975-6629)
- Joshua I. Chalif (ORCID: https://orcid.org/0000-0003-1769-5120)
- Hunter Mills
- Cathra Halabi (ORCID: https://orcid.org/0000-0002-0331-8183)
- Alí Salim (ORCID: https://orcid.org/0000-0002-4719-0505)
- Ahmad Mashlah
- Anthony M. DiGiorgio (ORCID: https://orcid.org/0000-0002-5710-691X)
- Muhammad M. Abd‐El‐Barr (ORCID: https://orcid.org/0000-0001-7151-2861)
- Yi Lü (ORCID: https://orcid.org/0000-0003-3979-5421)
- Rachel Grashow (ORCID: https://orcid.org/0000-0001-6961-0243)
- Sandro Marini (ORCID: https://orcid.org/0000-0001-9101-6996)
- Saef Izzy (ORCID: https://orcid.org/0000-0002-2822-6736)
- Akl C. Fahed (ORCID: https://orcid.org/0000-0002-4849-6389)
- Geoffrey A. Manley (ORCID: https://orcid.org/0000-0002-4950-4651)
- Benjamin E. Zusman (ORCID: https://orcid.org/0000-0003-2887-8934)
- Farid Radmanesh (ORCID: https://orcid.org/0000-0001-5431-0176)
- Taha Yahya (ORCID: https://orcid.org/0009-0009-6636-0117)
- Hasan A. Zaidi (ORCID: https://orcid.org/0000-0003-4570-1321)
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Duke University (US)
- University of California, San Francisco (US)
- Spaulding Rehabilitation Hospital (US)
- Massachusetts Mental Health Center (US)
- Massachusetts General Hospital (US)
- Neurological Surgery (US)
- University of Missouri (US)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.41157
- Citations
- 1
- Primary Topic
- Spinal Cord Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- U.S. Department of Defense
- Christopher and Dana Reeve Foundation
- Abbott Laboratories
- Massachusetts General Hospital
- Charles Koch Foundation
- Strong
- National Football League Players Association
- National Institutes of Health
- National Heart, Lung, and Blood Institute
- National Institute on Deafness and Other Communication Disorders