Prognostic value of preoperative ctDNA and pathological venous invasion for recurrence in EGFR-mutated non-small cell lung cancer
Preoperative ctDNA detection and pathological venous invasion provide complementary prognostic information, and venous invasion is an independent predictor of recurrence risk in EGFR-mutated NSCLC. Combined assessment may refine postoperative risk stratification and inform perioperative management.
Authors
- Noriyuki Ohkura (ORCID: https://orcid.org/0000-0002-6155-5101)
- Yuichi Tambo (ORCID: https://orcid.org/0000-0002-4095-4533)
- Seiji Yano (ORCID: https://orcid.org/0000-0002-6151-2988)
- Shigeki Nanjo (ORCID: https://orcid.org/0000-0001-8356-9849)
- Akihiro Nomura (ORCID: https://orcid.org/0000-0002-5774-8525)
- Satoshi Watanabe (ORCID: https://orcid.org/0000-0002-2579-8472)
- Kenta Yamamura (ORCID: https://orcid.org/0009-0009-8882-2773)
- Yuri Murase (ORCID: https://orcid.org/0009-0008-6328-4174)
- Takafumi Kobayashi (ORCID: https://orcid.org/0000-0002-2541-0589)
- Nanao Terada (ORCID: https://orcid.org/0000-0002-3055-7737)
- Hideharu Kimura (ORCID: https://orcid.org/0000-0002-6558-7012)
- Isao Matsumoto (ORCID: https://orcid.org/0000-0002-7995-9294)
- Tsukasa Ueda (ORCID: https://orcid.org/0000-0002-9704-379X)
- Hayato Koba (ORCID: https://orcid.org/0000-0002-7443-5432)
- Sachiko Arai
- Miki Abo (ORCID: https://orcid.org/0000-0002-2277-3843)
- Seiji Nomura
- Liu Yifeng (ORCID: https://orcid.org/0009-0000-2963-7265)
Institutions
- Kanazawa University (JP)
- Kanazawa University Hospital (JP)
- Life Science Institute (JP)
Publication Details
- Journal
- Lung Cancer
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1016/j.lungcan.2025.108818
- Citations
- 1
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52