Effect of Skeletal Muscle Mass and Its Associated Mediators on the Development of Steatotic Liver Disease: A Cohort Study in China
Relative skeletal muscle mass adjusted for weight or BMI, rather than height alone, better reflects protective effects against SLD. Mediation analysis reveals key metabolic factors linking muscle mass and liver health, offering insights into the pathogenic pathways involved in muscle-liver crosstalk.
Authors
- Lichang Zhong (ORCID: https://orcid.org/0000-0002-6701-7419)
- Weiping Jia (ORCID: https://orcid.org/0000-0002-6244-2168)
- Yuqian Bao (ORCID: https://orcid.org/0000-0002-4754-3470)
- Keqing Dong
- Lu Yang (ORCID: https://orcid.org/0000-0003-2532-8638)
- Xuhong Hou (ORCID: https://orcid.org/0000-0001-6156-5994)
- Rong Yu (ORCID: https://orcid.org/0000-0002-8488-0417)
- Xiaoqi Ye (ORCID: https://orcid.org/0000-0002-8703-9551)
- Wei Li (ORCID: https://orcid.org/0000-0001-7135-1033)
- Yebei Liang
- Feng Liang (ORCID: https://orcid.org/0000-0002-0854-231X)
- Fusong Jiang (ORCID: https://orcid.org/0000-0002-2765-0041)
Institutions
- Fujian Medical University (CN)
- Shanghai Jiao Tong University (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
- Shanghai Sixth People's Hospital (CN)
- Community Health Center (US)
- Shanghai Clinical Research Center (CN)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1002/jcsm.70093
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35