Blood metabolites mediate gut microbiota effects on depression: A Mendelian randomization study
Our findings provide genetic evidence for the causal involvement of specific GM in Depression, mediated by distinct metabolic pathways, suggesting potential microbiota-based interventions for Depression treatment.
Authors
- Shasha Zhao (ORCID: https://orcid.org/0000-0003-4886-3182)
- Xueyan Li (ORCID: https://orcid.org/0000-0003-0457-7846)
- Yaowen Zhang (ORCID: https://orcid.org/0000-0002-2379-6174)
- Hongjian Liu (ORCID: https://orcid.org/0000-0002-3346-9193)
Institutions
- Cangzhou Central Hospital (CN)
Publication Details
- Journal
- Journal of Affective Disorders
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1016/j.jad.2025.120478
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00