Elevated levels of cleaved soluble forms of urokinase-type plasminogen activator receptor are associated with poor survival in advanced pancreatic cancer
Elevated plasma levels of uPAR(I) and suPAR(I-III+II-III) were associated with poor survival in patients with advanced PDAC independent of CA19-9 levels. These biomarkers have a potential prognostic value in this population.
Authors
- I.J. Christensen
- Astrid Z. Johansen (ORCID: https://orcid.org/0000-0002-4948-6799)
- Fahimeh Andersen
- I‐Ming Chen (ORCID: https://orcid.org/0000-0002-4831-3781)
- David G. Calatayud (ORCID: https://orcid.org/0000-0003-2633-2989)
- Rikke Løvendahl Eefsen (ORCID: https://orcid.org/0000-0003-1421-1792)
- J.S. Johansen
- Per Pfeiffer (ORCID: https://orcid.org/0000-0002-2925-0586)
- G. Høyer-Hansen
Institutions
- University of Copenhagen (DK)
- Odense University Hospital (DK)
- Herlev Hospital (DK)
- Gentofte Hospital (DK)
- Zealand University Hospital (DK)
Publication Details
- Journal
- European Journal of Cancer
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1016/j.ejca.2025.116095
- Primary Topic
- Protease and Inhibitor Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Gentofte Hospital
- Herlev Hospital