Laryngopharyngeal reflux disease: a pilot study with a new multicomponent
This study provides the first clinical evidence that the tested multicomponent device is effective and safe in improving both subjective symptoms and objective signs of LPRD. The observed greater benefit in patients with recent symptom onset supports early intervention. These findings are consistent with current recommendations that prioritize non-acid-suppressive agents in LPRD management. Further randomized controlled trials are warranted.
Authors
- Andrea Nacci (ORCID: https://orcid.org/0000-0002-5921-0964)
- Giorgio Ciprandi (ORCID: https://orcid.org/0000-0001-7016-8421)
- Luca Bastiani (ORCID: https://orcid.org/0000-0003-3467-7362)
- Andrea Galli (ORCID: https://orcid.org/0000-0003-0719-3135)
- Sara Capobianco
Institutions
- University of Pisa (IT)
- Istituto di Fisiologia Clinica (IT)
- Casa di Cura Villa Garda (IT)
- Casa di Cura Columbus (IT)
Publication Details
- Journal
- Panminerva Medica
- Published
- 2025-11-04
- DOI
- https://doi.org/10.23736/s0031-0808.25.05387-x
- Primary Topic
- Gastroesophageal reflux and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00