Inhibition of ATP citrate lyase does not affect muscle mitochondrial activity in apoE-/- mice
In apoE<sup>-/-</sup> mice, bempedoic acid positively impacts plaque burden while preventing skeletal muscle mitochondrial dysfunction.
Authors
- Alessandra Stefania Rizzuto (ORCID: https://orcid.org/0000-0002-5704-9230)
- Valerio Magnaghi (ORCID: https://orcid.org/0000-0002-6903-7042)
- Cesare R. Sirtori (ORCID: https://orcid.org/0000-0001-6224-5538)
- Massimiliano Ruscica (ORCID: https://orcid.org/0000-0002-0195-7061)
- Marco Busnelli (ORCID: https://orcid.org/0000-0003-3245-2872)
- Chiara Pavanello (ORCID: https://orcid.org/0000-0001-5892-9857)
- Elena Osto (ORCID: https://orcid.org/0000-0001-8196-5696)
- Chiara Macchi (ORCID: https://orcid.org/0000-0002-5919-989X)
- Elsa Franchi (ORCID: https://orcid.org/0000-0001-7993-0486)
- Alberto Corsini (ORCID: https://orcid.org/0000-0002-9912-9482)
- Tasnim Mohamed (ORCID: https://orcid.org/0000-0002-1144-4876)
- Stefano Carugo (ORCID: https://orcid.org/0000-0002-5166-0899)
- Giulia Chiesa (ORCID: https://orcid.org/0000-0001-5553-1210)
- Juergen Gindlhuber (ORCID: https://orcid.org/0000-0002-6155-5208)
- Isabella Fichtner
- Simone Nerini (ORCID: https://orcid.org/0009-0006-5799-3666)
Institutions
- University of Milan (IT)
- Medical University of Graz (AT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Ospedale Maggiore (IT)
- Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1016/j.biopha.2025.118726
- Citations
- 1
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.81