Accounting for social and environmental drivers of neurodevelopment: lessons from a pilot study in a pediatric Colombian cohort

Maternal education, dietary diversity, total home resources, and location account for approximately 50% of the neurodevelopmental variability of children from urban and rural Colombian cohorts. Typically developing children from a rural community in Colombia have a lower Full-Scale IQ than peers from urban cities, even after including multiple covariates. Future research should continue to study the multiple factors that impact neurodevelopment, particularly in low- and middle-income countries. Well-matched control populations and the use of culturally appropriate, validated assessments are important to minimize confounding factors in neurodevelopmental outcomes research, as statistical correction is not sufficient to fully account for these differences.

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Publication Details

Journal
Pediatric Research
Published
2025-11-04
DOI
https://doi.org/10.1038/s41390-025-04452-9
Primary Topic
Infant Development and Preterm Care
Type
article
Field-Weighted Citation Impact
0.00

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article

Accounting for social and environmental drivers of neurodevelopment: lessons from a pilot study in a pediatric Colombian cohort

Pablo Reyes, Colleen Peyton, Sarah B. Mulkey, Meagan E. Williams et al.
Pediatric Research
Infant Development and Preterm Care
article

Accounting for social and environmental drivers of neurodevelopment: lessons from a pilot study in a pediatric Colombian cohort

Pablo Reyes, Colleen Peyton, Sarah B. Mulkey, Meagan E. Williams, Michael E. Msall, Elizabeth Corn, Margarita Arroyave‐Wessel, Madison M. Berl, Carlos Curé, Heather Gordish‐Dressman, Regan Andringa-Seed, Luisa Suárez
article en

Abstract

Maternal education, dietary diversity, total home resources, and location account for approximately 50% of the neurodevelopmental variability of children from urban and rural Colombian cohorts. Typically developing children from a rural community in Colombia have a lower Full-Scale IQ than peers from urban cities, even after including multiple covariates. Future research should continue to study the multiple factors that impact neurodevelopment, particularly in low- and middle-income countries. Well-matched control populations and the use of culturally appropriate, validated assessments are important to minimize confounding factors in neurodevelopmental outcomes research, as statistical correction is not sufficient to fully account for these differences.

Pediatric Research
Northwestern University (US), Children's National (US), George Washington University (US), Pontificia Universidad Javeriana (CO), University of Atlántico (CO), Comer Children's Hospital (US)
Children's National Hospital, National Institutes of Health
Openalex Percentile: Top 55%
Infant Development and Preterm Care
DOIOpen Access PDFOpenAlex
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