Technical systematic review supporting the 2025 AASLD Practice Guideline on management of chronic hepatitis B
Despite low certainty, the findings support shared decision-making in high-risk horizontal transmission scenarios or in treating individuals in the immune tolerance phase, caution in discontinuing antiviral therapy in virologically suppressed individuals without HBsAg loss, and tailored HCC surveillance for those with co-infection or cirrhosis.
Authors
- Samer Saadi (ORCID: https://orcid.org/0000-0001-9225-1197)
- Joseph K. Lim (ORCID: https://orcid.org/0000-0003-1126-8128)
- Marc G. Ghany (ORCID: https://orcid.org/0000-0003-2837-0188)
- Norah A. Terrault (ORCID: https://orcid.org/0000-0003-4143-1950)
- Tarek Nayfeh (ORCID: https://orcid.org/0000-0001-9052-5537)
- Khorshid Mohammad (ORCID: https://orcid.org/0000-0002-3568-7282)
- A Y Kim
- Mohamed O. Seisa (ORCID: https://orcid.org/0000-0002-5179-4264)
- Amy S. Tang (ORCID: https://orcid.org/0000-0002-8151-2686)
- Alzhraa Salah Abbas (ORCID: https://orcid.org/0000-0003-3975-1496)
- Mohammad Hassan Murad (ORCID: https://orcid.org/0000-0001-5502-5975)
- Calvin Q. Pan (ORCID: https://orcid.org/0000-0002-3723-6688)
- Farah Fleti
- Larry J. Prokop (ORCID: https://orcid.org/0000-0002-7197-7260)
- Anna S. Lok (ORCID: https://orcid.org/0000-0002-5811-6845)
- Bashar Hasan (ORCID: https://orcid.org/0000-0001-9531-4990)
- Moustafa Hegazi (ORCID: https://orcid.org/0009-0006-8190-3915)
- Mark S. Sulkowski
- Jordan J. Feld
- Mohamed Abusalih (ORCID: https://orcid.org/0009-0006-3326-301X)
- Mindie H. Nguyen
- Adel Kabbara Allababidi (ORCID: https://orcid.org/0009-0004-3354-4562)
Institutions
- University of Southern California (US)
- University Health Network (CA)
- Mayo Clinic (US)
- Harvard University (US)
- Johns Hopkins University (US)
- University of Michigan (US)
- Johns Hopkins Medicine (US)
- WinnMed (US)
- Yale Cancer Center (US)
- Yale University (US)
- NYU Langone Health (US)
- Massachusetts General Hospital (US)
- National Institute of Diabetes and Digestive and Kidney Diseases (US)
- Stanford Medicine (US)
- Mayo Clinic in Florida (US)
- Toronto Liver Centre (CA)
- New York University (US)
- Stanford University (US)
Publication Details
- Journal
- Hepatology
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1097/hep.0000000000001584
- Citations
- 1
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.35