The Potential of Parkia platycephala from Use to Cure
Parkia platycephala has emerged as a promising medicinal species, attracting growing scientific interest due to its richness in bioactive compounds such as phenolic acids, flavonoids, tannins, saponins, terpenes, and lectins, present across different parts of the plant. Studies to date have highlighted its varied biological activities, including antioxidant, anti-inflammatory, antimicrobial, and antitumoral properties. Additionally, these compounds have been shown to increase the efficacy of conventional therapeutic drugs and reduce resistance to their effects. Given the breadth and relevance of these findings, compiling and systematizing the available data on P. platycephala is essential. A comprehensive synthesis not only facilitates a better understanding of the plant’s phytochemical and pharmacological potential but also lays the groundwork for the development of innovative, multi-target therapeutic strategies. This effort is particularly relevant in addressing current challenges in treating infections, inflammatory disorders, and cancer, thereby reinforcing the species’ value as a strategic resource for future drug discovery and integrative medicine.
Authors
- Joana B. Nunes (ORCID: https://orcid.org/0000-0002-8968-9670)
- Rui Medeiros (ORCID: https://orcid.org/0000-0003-3010-8373)
- Cláudia Quintino da Rocha (ORCID: https://orcid.org/0000-0002-3578-1869)
- Fátima Cerqueira (ORCID: https://orcid.org/0000-0003-4513-4654)
- Matheus Chagas Melonio
Institutions
- Fernando Pessoa University (PT)
- Universidade do Porto (PT)
- Instituto Português de Oncologia Francisco Gentil (PT)
- Universidade Federal do Maranhão (BR)
- Polytechnic Institute of Porto (PT)
Publication Details
- Journal
- Compounds
- Published
- 2025-11-04
- DOI
- https://doi.org/10.3390/compounds5040047
- Primary Topic
- African Botany and Ecology Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico