Prognostic impact of extranodal extension in oral cavity cancers: a retrospective analysis and implications for treatment intensification
ENE significantly worsens OS and DFS in OCSCC patients, even with standard adjuvant chemoradiotherapy. These findings support the need for treatment intensification strategies, such as radiation dose escalation and/or additional systemic therapy, in this high-risk group.
Authors
- Alok Goel (ORCID: https://orcid.org/0000-0002-3202-6198)
- Ankur Dwivedi (ORCID: https://orcid.org/0000-0002-2823-527X)
- Tapas Dora (ORCID: https://orcid.org/0000-0002-6159-7344)
- Ashish Gulia (ORCID: https://orcid.org/0000-0002-5133-7442)
- Sankalp Sancheti (ORCID: https://orcid.org/0000-0001-5810-8733)
- Pragyat Thakur (ORCID: https://orcid.org/0000-0001-7486-9671)
- Anshul Singla
- Arshdeep Kaur (ORCID: https://orcid.org/0000-0002-8956-4990)
- I Vedamanasa (ORCID: https://orcid.org/0000-0001-7668-3045)
Institutions
- Bhabha Hospital (IN)
- Cancer Hospital and Research Institute (IN)
Publication Details
- Journal
- Journal of Cancer Research and Clinical Oncology
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1007/s00432-025-06337-0
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00