Rare presentation of thyrotoxicosis due to gestational trophoblastic disease – a case report

Abstract Gestational trophoblastic disease (GTD) usually presents early in pregnancy with mild symptoms. Clinical thyrotoxicosis is rare, with thyroid storm only reported in previous case reports. GTD presenting with thyroid storm is potentially life-threatening, and a high index of suspicion is necessary to avoid morbidity and mortality. We report a case of GTD presenting with severe thyrotoxicosis and a negative pregnancy test due to the hook effect. Point-of-care ultrasound (POCUS) was instrumental in making the diagnosis.