Histopathological and Molecular Predictors of the First Site of Dissemination in Non-Small Cell Lung Cancer
The first metastatic site in NSCLC follows histology-specific patterns, with adenocarcinoma favoring hematogenous spread and squamous carcinoma showing locoregional involvement. Molecular status further refines these patterns in adenocarcinoma. Incorporating histology into baseline staging may improve diagnostic efficiency and prognostic accuracy.
Authors
- Alina Gabriela Negru (ORCID: https://orcid.org/0000-0001-9838-744X)
- Anca Maria Cîmpean (ORCID: https://orcid.org/0000-0002-9530-022X)
- Mihaela Pasca Fenesan (ORCID: https://orcid.org/0000-0002-3366-8264)
- Razvan Constantin Vonica
- Andrei Alexandru Cosma (ORCID: https://orcid.org/0009-0007-8553-1183)
- Dea Nagy
- Vlad-Norin Vornicu
Institutions
- Lucian Blaga University of Sibiu (RO)
- Polytechnic University of Timişoara (RO)
- Victor Babeș University of Medicine and Pharmacy Timișoara (RO)
Publication Details
- Journal
- Current Oncology
- Published
- 2025-11-04
- DOI
- https://doi.org/10.3390/curroncol32110617
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00