Behavioral and Emotional Challenges in Children With Spinal Muscular Atrophy
The study found clinically significant level of emotional and behavioral dysregulation in children/young people with SMA in all categories of motor function, and with negative impact on everyday life. In the context of changing phenotypes and function with treatment, these were evident across varying severities of motor function. These findings support routine mental health surveillance as a means of early identification and intervention, alongside the provision of psychological support to optimize health outcomes.
Authors
- Esther Tantsis (ORCID: https://orcid.org/0000-0003-3414-3889)
- Karen Herbert
- Didu Kariyawasam (ORCID: https://orcid.org/0000-0002-4176-4010)
- Michelle A. Farrar (ORCID: https://orcid.org/0000-0002-4472-0902)
- Lakshmi Balaji (ORCID: https://orcid.org/0000-0001-9286-900X)
- Hugo Sampaio
Institutions
- Children's Hospital at Westmead (AU)
- Sydney Children's Hospital (AU)
- Sydney Children’s Hospitals Network (AU)
Publication Details
- Journal
- Pediatric Neurology
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1016/j.pediatrneurol.2025.10.029
- Primary Topic
- Neurogenetic and Muscular Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Australian Government
- University of New South Wales
- Medical Research Council
- National Health and Medical Research Council