MYEOV Is a Novel Marker of Differentiated Corneal Epithelium
Our study revealed specific high MYEOV expression in KRT12-positive corneal epithelial cells among surface ectoderm-derived epithelia. Similar to KRT12, MYEOV expression is regulated by PAX6 and KLF4. Functionally, MYEOV regulates the proliferation of transient amplifying cells in the cornea.
Authors
- Vickie Y. Jo (ORCID: https://orcid.org/0000-0003-4808-2714)
- Gëorge F. Murphy (ORCID: https://orcid.org/0000-0001-9362-5146)
- Yoshiko Fukuda
- Natasha Y. Frank (ORCID: https://orcid.org/0000-0001-8196-0449)
- Chao Zhang (ORCID: https://orcid.org/0000-0001-8019-7998)
- Yuzuru Sasamoto (ORCID: https://orcid.org/0009-0006-3249-8546)
- Christine G. Lian (ORCID: https://orcid.org/0000-0003-4626-1612)
- Bruce R. Ksander (ORCID: https://orcid.org/0000-0001-5546-0360)
- Markus H. Frank (ORCID: https://orcid.org/0000-0002-1312-0488)
Institutions
- Boston University (US)
- Edith Cowan University (AU)
- Brigham and Women's Hospital (US)
- Massachusetts Eye and Ear Infirmary (US)
- Boston Children's Hospital (US)
- Harvard University (US)
- University of Washington (US)
- VA Boston Healthcare System (US)
- Harvard Stem Cell Institute (US)
- Smith-Kettlewell Eye Research Institute (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1167/iovs.66.14.7
- Citations
- 1
- Primary Topic
- Kruppel-like factors research
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Eye Bank Association of America
- Massachusetts Lions Eye Research Fund
- University of Washington
- Japan Eye Bank Association
- National Institutes of Health
- Harvard Stem Cell Institute