AQP5 Regulates Corneal Nerve Distribution Through NETRIN-1 and SLIT3
AQP5 deficiency disrupts corneal nerve architecture and may contribute to NK. AQP5 regulates corneal nerve distribution via the JUN-D-Ntn1/Slit3 pathway. These findings identify potential molecular targets for the prevention and treatment of NK.
Authors
- Guohu Di (ORCID: https://orcid.org/0000-0001-9940-730X)
- Yu Gu (ORCID: https://orcid.org/0000-0002-2707-0063)
- Dianqiang Wang
- Fei Li (ORCID: https://orcid.org/0009-0004-7499-7197)
- Peng Chen (ORCID: https://orcid.org/0000-0001-7522-3813)
- Yaning Liu (ORCID: https://orcid.org/0000-0002-9926-6460)
- Wenbo Yan (ORCID: https://orcid.org/0000-0002-0860-8702)
- Peirong Song
- Wenshuo Han
Institutions
- Qingdao University (CN)
- Central South University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1167/iovs.66.14.6
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 0.00