Therapeutic Potential of Graphene Quantum Dots on Pterygium Cells
GQDs suppress multiple pathologic features of pterygium, including selective cytotoxicity, downregulation of key molecular mediators (cyclin D1, periostin, MMP-3, and MMP-9), and a novel mechanism involving microtubule fragmentation. These findings support the potential of GQDs as a noninvasive therapeutic strategy to suppress pterygium progression and decrease postoperative recurrence.
Authors
- Donghoon Koo (ORCID: https://orcid.org/0000-0002-3061-6880)
- Hyun Seung Yang (ORCID: https://orcid.org/0000-0002-0470-676X)
- Minji Kim (ORCID: https://orcid.org/0000-0003-2322-9900)
- Jeongmin Kim (ORCID: https://orcid.org/0000-0002-1235-1487)
Institutions
- Seoul National University (KR)
- Advanced Institute of Convergence Technology (KR)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1167/iovs.66.14.9
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00