Comparative evaluation of transforaminal lumbar interbody fusion and instrumented posterolateral fusion in Grade I/II Spondylolisthesis: A prospective study

The optimal surgical approach between Transforaminal Lumbar Interbody Fusion (TLIF) and Posterolateral Fusion (PLF) for Grade I/II spondylolisthesis remains unclear. Therefore, it is of interest to compare clinical and radiological outcomes of TLIF versus PLF in patients with Grade I/II spondylolisthesis. PLF achieved better 6-month functional outcomes (ODI 12.95 ± 2.54 vs 17.83 ± 1.95, p<0.001) and greater slip reduction (48.45% vs 40.20%, p<0.001). TLIF provided superior early leg pain relief at 3 months (VAS 2.03 ± 0.80 vs 2.50 ± 0.91, p=0.015) and better DPQ scores. Complication and fusion rates were similar between groups. Both techniques are effective, with choice guided by patient profile and clinical priorities.