Prognostic and predictive value of AXL and C-MET in patients with rectal cancer
AXL serum levels in the rectal cancer cohort were significantly different from healthy subjects but did not correlate with tumor stage or survival during and after neoadjuvant/adjuvant therapy. Soluble C-MET levels in the blood, influenced by neoadjuvant chemoradiotherapy, may serve as a predictive marker for treatment response.
Authors
- Carmen Austrália Paredes Marcondes Ribas (ORCID: https://orcid.org/0000-0002-6195-046X)
- Jurandir Marcondes Ribas-Filho (ORCID: https://orcid.org/0000-0002-5251-7672)
- Bülent Polat (ORCID: https://orcid.org/0000-0003-4677-424X)
- Ana Maria Waaga Gasser (ORCID: https://orcid.org/0000-0001-5437-716X)
- Osvaldo Malafaia (ORCID: https://orcid.org/0000-0002-1829-7071)
- R. Lissner (ORCID: https://orcid.org/0000-0002-4461-5125)
- M Gasser (ORCID: https://orcid.org/0000-0002-0797-169X)
- Sudipta Tripathi (ORCID: https://orcid.org/0000-0001-7729-9002)
- Thomas Boeldicke (ORCID: https://orcid.org/0000-0003-2869-1133)
- Efstathia N Doelken (ORCID: https://orcid.org/0009-0001-1683-6780)
Institutions
- Brigham and Women's Hospital (US)
- University of Massachusetts Chan Medical School (US)
- University of Würzburg (DE)
- Evangelical Theological Faculty (BE)
- Augenklinik Universitätsklinikum Würzburg (DE)
- Helmholtz Centre for Infection Research (DE)
- Helmholtz Institute for RNA-based Infection Research (DE)
- Universitätsklinikum Würzburg (DE)
- Faculdade Evangélica do Paraná (BR)
Publication Details
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1590/0102-67202025000049e1918
- Primary Topic
- Phagocytosis and Immune Regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00