Genome sequences of two highly colistin-resistant <i>Pseudomonas aeruginosa</i> clinical isolates from the cystic fibrosis lung
The genomes of two highly colistin-resistant strains of <i>Pseudomonas aeruginosa</i> (MICs ≥ 1,024 mg/mL) isolated from cystic fibrosis lung infections were sequenced and analyzed. Genes associated with colistin resistance (<i>pmrAB</i>, <i>phoPQ</i>) showed unique mutations compared to other strains with similar resistance levels.
Authors
- Yohei Doi (ORCID: https://orcid.org/0000-0002-9620-2525)
- Christian Melander (ORCID: https://orcid.org/0000-0001-8271-4696)
- Anne E. Mattingly (ORCID: https://orcid.org/0009-0001-7668-4942)
Institutions
- University of Notre Dame (US)
- University of Pittsburgh (US)
- National Center for Infectious Diseases (US)
Publication Details
- Journal
- Microbiology Resource Announcements
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1128/mra.00558-25
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00