A STUDY OF THE CLINICAL PROFILE OF GASTROINTESTINAL AND PRIMARY SPLENIC LYMPHOMA CASES AT A TERTIARY CARE HOSPITAL

Background: Gastrointestinal lymphomas are the most common extranodal lymphomas, while primary splenic lymphomas remain rare and diagnostically challenging. To eva Objectives: luate the clinical features, diagnostic findings, and treatment outcomes of gastrointestinal and primary splenic lymphomas in a tertiary care hospital. Twenty patient Methods: s with histologically confirmed non-Hodgkin lymphoma involving the gastrointestinal tract or spleen were analyzed. Clinical presentation, investigations, histology, and outcomes were studied. Diffuse large B-cell lymphoma was Results: the predominant subtype. PET-CT and endoscopy were valuable diagnostic tools. Patients treated with combined surgery and chemotherapy had better survival compared to those receiving chemotherapy alone. PET-CT–based staging showed significant correlation with improved prognosis (p=0.047). Early diagnosis and multimodality manageme Conclusion: nt improve outcomes in gastrointestinal and splenic lymphomas. PET-CT serves as an important aid in evaluation and follow-up.