FROM THE PERIPHERY TO THE CORTEX: UNRAVELING THE PUZZLE OF FOCAL SEIZURES IN NEUROFIBROMATOSIS

Neurofibromatosis type 1 (NF1) is an autosomal dominant neurocutaneous disorder with a wide spectrum of clinical manifestations. Among its neurological complications, seizures are relatively uncommon but clinically significant.We present the case of a 52-year-old man with focal seizures in the context of NF1. The patient reported involuntary movements of the right upper and lower limb for 4 days, accompanied by headaches. Physical examination revealed multiple café-au-lait spots and cutaneous neurofibromas. MRI brain was consistent with NF1. Family history was also positive.This case highlights the neurological involvement in NF1 and underscores the importance of multidisciplinary management.