Orthopedic implant-related ESBL <i>Klebsiella pneumoniae</i> infection post-ORIF surgery: a case report

Implant-related bacterial infection remains a major issue. Particularly caused by <i>Klebsiella pneumoniae</i>. A 35-year-old female, 3 months post open reduction and internal fixation for right cruris fracture, presented with infection symptoms. She underwent implant removal and surgical debridement. Microbiological samples from pus, infected tissue, and implant confirmed <i>K. pneumoniae</i> infection with Extended Spectrum Beta-Lactamase production. Post-surgery, she received meropenem for 5 days, followed by oral one-gram fosfomycin for 2 days. No signs of infection were detected within a week. Regardless of healing process is achieved; removing the implant will improve the outcome. The surface of implants is prone to bacterial colonization, which can lead to the development of antibiotic resistance. This paper presents a case of implant-related bacterial infection. Implant-related <i>K. pneumoniae</i> infection could lead to antimicrobial-resistant organisms that increase the probability of difficult-to-treat conditions. Removing the implant, combined with antibiotic delivery, could be the best approach.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-09-30
DOI
https://doi.org/10.1093/jscr/rjaf860
Primary Topic
Orthopedic Infections and Treatments
Type
article
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article

Orthopedic implant-related ESBL Klebsiella pneumoniae infection post-ORIF surgery: a case report

Achmad Zaki, A. Irfan, Erike A. Suwarsono, Harningtyas A Jasmin
Journal of Surgical Case Reports
Orthopedic Infections and Treatments
article

Orthopedic implant-related ESBL Klebsiella pneumoniae infection post-ORIF surgery: a case report

Achmad Zaki, A. Irfan, Erike A. Suwarsono, Harningtyas A Jasmin
article en

Abstract

Implant-related bacterial infection remains a major issue. Particularly caused by <i>Klebsiella pneumoniae</i>. A 35-year-old female, 3 months post open reduction and internal fixation for right cruris fracture, presented with infection symptoms. She underwent implant removal and surgical debridement. Microbiological samples from pus, infected tissue, and implant confirmed <i>K. pneumoniae</i> infection with Extended Spectrum Beta-Lactamase production. Post-surgery, she received meropenem for 5 days, followed by oral one-gram fosfomycin for 2 days. No signs of infection were detected within a week. Regardless of healing process is achieved; removing the implant will improve the outcome. The surface of implants is prone to bacterial colonization, which can lead to the development of antibiotic resistance. This paper presents a case of implant-related bacterial infection. Implant-related <i>K. pneumoniae</i> infection could lead to antimicrobial-resistant organisms that increase the probability of difficult-to-treat conditions. Removing the implant, combined with antibiotic delivery, could be the best approach.

Journal of Surgical Case ReportsVol. 2025(10)
University of London (GB), Syarif Hidayatullah State Islamic University Jakarta (ID), London School of Hygiene & Tropical Medicine (GB)
Openalex Percentile: Top 50%
Orthopedic Infections and Treatments
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