Alisol A Exerts Anti-Proliferative Activity against Human Oral Cancer Cells through Triggering JNK/p38 MAPK-Mediated Apoptotic Cascade
Our findings demonstrate that Alisol A exerts potent anticancer effects on oral cancer cells by inducing caspase-dependent apoptosis via activation of the JNK and p38 signaling pathways. These results suggest that Alisol A may have therapeutic potential for the treatment of oral cancer.
Authors
- Shao‐Hsuan Kao (ORCID: https://orcid.org/0000-0002-4929-3858)
- Yi‐Tzu Chen (ORCID: https://orcid.org/0000-0002-6022-7085)
- Chun-Yi Chuang
- Chih‐Hsin Tang (ORCID: https://orcid.org/0000-0002-7113-8352)
- Wei‐En Yang
- Chun‐Wen Su (ORCID: https://orcid.org/0009-0008-5271-5995)
- Chiao-Wen Lin
- Shun-Fa Yang
Institutions
- Asia University (TW)
- China Medical University (TW)
- Chung Shan Medical University Hospital (TW)
- Chung Shan Medical University (TW)
Publication Details
- Journal
- Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
- Published
- 2025-01-01
- DOI
- https://doi.org/10.32604/or.2025.069877
- Primary Topic
- Cell death mechanisms and regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00