Association between hepatitis B virus markers and liver fibrosis staging in patients with chronic hepatitis B

HBcAb is negatively correlated with HBV-DNA and HBsAg but positively associated with LF staging. All three markers are valuable in assessing LF staging, and their combined use presents the highest diagnostic efficacy. Importantly, a high HBcAb/low HBV-DNA profile markedly increased fibrosis progression risks in CHB-affected individuals.

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Publication Details

Journal
World Journal of Gastrointestinal Surgery
Published
2025-10-23
DOI
https://doi.org/10.4240/wjgs.v17.i10.106414
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Association between hepatitis B virus markers and liver fibrosis staging in patients with chronic hepatitis B

Kai Wang, Xiaojing Huang, Xiao Zheng
World Journal of Gastrointestinal Surgery
Hepatitis B Virus Studies
article

Association between hepatitis B virus markers and liver fibrosis staging in patients with chronic hepatitis B

Kai Wang, Xiaojing Huang, Xiao Zheng
article en

Abstract

HBcAb is negatively correlated with HBV-DNA and HBsAg but positively associated with LF staging. All three markers are valuable in assessing LF staging, and their combined use presents the highest diagnostic efficacy. Importantly, a high HBcAb/low HBV-DNA profile markedly increased fibrosis progression risks in CHB-affected individuals.

World Journal of Gastrointestinal SurgeryVol. 17(10)
Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
Openalex Percentile: Top 57%
Hepatitis B Virus Studies
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