Efficacy of extracellular vesicles derived from mesenchymal stromal cells in regulating senescence: <i>In vitro</i> and <i>in vivo</i> insights
These findings indicate that MSC-EVs can partially alleviate D-gal-induced senescence by reducing oxidative stress and regulating metabolism. Overall, these findings strongly suggest that MSC-EVs hold promise for aging therapy.
Authors
- Wanqiang Zhuang
- Shuangshuang Yang (ORCID: https://orcid.org/0000-0003-0871-6356)
- Yi Tan (ORCID: https://orcid.org/0000-0002-0990-0860)
- Siyu Chen (ORCID: https://orcid.org/0000-0003-4565-4772)
- Ya Liu (ORCID: https://orcid.org/0000-0002-0750-4979)
- Jing Han (ORCID: https://orcid.org/0000-0003-1460-0114)
- Hongyu Ma (ORCID: https://orcid.org/0000-0003-2299-503X)
- Huizhen Guo (ORCID: https://orcid.org/0000-0001-6895-9953)
- Li Deng (ORCID: https://orcid.org/0000-0002-5639-4104)
Institutions
- Qilu University of Technology (CN)
- Shandong Provincial Hospital (CN)
- Shandong Lianxing Energy Group (China) (CN)
- Shandong Provincial QianFoShan Hospital (CN)
- Qilu Hospital of Shandong University (CN)
- First Affiliated Hospital of Jinan University (CN)
- Shandong First Medical University (CN)
- Ocean University of China (CN)
Publication Details
- Journal
- World Journal of Stem Cells
- Published
- 2025-10-24
- DOI
- https://doi.org/10.4252/wjsc.v17.i10.110445
- Citations
- 2
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.61