Cardiac transthyretin amyloidosis in aortic valve replacement: RAISE score performance in the postoperative setting

After AVR, the complex RAISE Score showed lower sensitivity than originally reported, while simpler parameters demonstrated comparable predictive value for ATTR-CM screening. Advanced age, CTS history and elevated NT-proBNP levels seem most valuable for identifying candidates for bone scintigraphy.

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Publication Details

Journal
Clinical Research in Cardiology
Published
2025-11-04
DOI
https://doi.org/10.1007/s00392-025-02766-6
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
0.00

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article

Cardiac transthyretin amyloidosis in aortic valve replacement: RAISE score performance in the postoperative setting

Stephan Nienaber, Roman Pfister, Μαρία Παπαθανασίου, Stephan Baldus et al.
Clinical Research in Cardiology
Amyloidosis: Diagnosis, Treatment, Outcomes
article

Cardiac transthyretin amyloidosis in aortic valve replacement: RAISE score performance in the postoperative setting

Stephan Nienaber, Roman Pfister, Μαρία Παπαθανασίου, Stephan Baldus, Matthieu Schäfer, Sascha Macherey‐Meyer, Jasper F. Nies, Richard J. Nies, Fabian Voß, Clemens Metze, Katharina Seuthe, Matti Adam, Merve Kural, Can Öztürk, Svenja Ney, Amin Polzin, Jan Grobecker, Friedrich Gruenagel
article en

Abstract

After AVR, the complex RAISE Score showed lower sensitivity than originally reported, while simpler parameters demonstrated comparable predictive value for ATTR-CM screening. Advanced age, CTS history and elevated NT-proBNP levels seem most valuable for identifying candidates for bone scintigraphy.

Clinical Research in Cardiology
Goethe University Frankfurt (DE), University Hospital Bonn (DE), Düsseldorf University Hospital (DE), University Hospital Frankfurt (DE), University Hospital Cologne (DE), Heinrich Heine University Düsseldorf (DE)
Pfizer
Openalex Percentile: Top 71%
Amyloidosis: Diagnosis, Treatment, Outcomes
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