Differentiation of light chain cardiac amyloidosis and hypertrophic cardiomyopathy by ensemble machine learning-based radiomic analysis of cardiac magnetic resonance

An ensemble ML model with competitive diagnostic accuracy was proposed to differentiate AL-CA from HCM patients and healthy controls.

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Publication Details

Journal
Orphanet Journal of Rare Diseases
Published
2025-11-04
DOI
https://doi.org/10.1186/s13023-025-03947-2
Primary Topic
Amyloidosis: Diagnosis, Treatment, Outcomes
Type
article
Field-Weighted Citation Impact
0.00

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article

Differentiation of light chain cardiac amyloidosis and hypertrophic cardiomyopathy by ensemble machine learning-based radiomic analysis of cardiac magnetic resonance

Ming Wu, Zhuang Tian, Shengsheng Zhuang, Yuanqiang Zhang et al.
Orphanet Journal of Rare Diseases
Amyloidosis: Diagnosis, Treatment, Outcomes
article

Differentiation of light chain cardiac amyloidosis and hypertrophic cardiomyopathy by ensemble machine learning-based radiomic analysis of cardiac magnetic resonance

Ming Wu, Zhuang Tian, Shengsheng Zhuang, Yuanqiang Zhang, Yubo Guo, Jian Li, Yining Wang, Ting Chen, Shuyuan Zhang, Xiao Li, Yuze Gao
article en

Abstract

An ensemble ML model with competitive diagnostic accuracy was proposed to differentiate AL-CA from HCM patients and healthy controls.

Orphanet Journal of Rare DiseasesVol. 20(1)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN), Beijing Academy of Artificial Intelligence (CN), Tsinghua University (CN)
Chinese Academy of Medical Sciences, Peking Union Medical College Hospital, Fundamental Research Funds for the Central Universities
Openalex Percentile: Top 71%
Amyloidosis: Diagnosis, Treatment, Outcomes
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