Reduced Sensorimotor, Working Memory, and Episodic Memory Abilities in Aging Female FMR1 Premutation Carriers with and Without Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS)
Together, these findings indicate that FXTAS+ females exhibit distinct motor and cognitive impairments, underscoring the value of quantitative behavioral measures for detecting and tracking neurodegenerative progression in female premutation carriers.
Authors
- Kristen C. McGatlin
- Flora Tassone (ORCID: https://orcid.org/0000-0002-6388-9180)
- Kathryn E. Unruh (ORCID: https://orcid.org/0000-0001-6745-5550)
- Scott Peterson (ORCID: https://orcid.org/0000-0002-2114-202X)
- Robin L. Shafer (ORCID: https://orcid.org/0000-0002-7211-3501)
- Heather R. Bailey (ORCID: https://orcid.org/0000-0002-0953-3212)
- Cassandra J. Stevens (ORCID: https://orcid.org/0009-0006-3097-0608)
- Richard Dubinsky (ORCID: https://orcid.org/0000-0001-8496-2909)
- Matthew W. Mosconi (ORCID: https://orcid.org/0000-0002-1981-6777)
- Andrea P. Lee
- Randi J. Hagerman (ORCID: https://orcid.org/0000-0001-5029-8448)
Institutions
- University of Kansas (US)
- Kansas State University (US)
- University of Kansas Medical Center (US)
- University of California, Davis (US)
Publication Details
- Journal
- Genes
- Published
- 2025-11-04
- DOI
- https://doi.org/10.3390/genes16111331
- Citations
- 1
- Primary Topic
- Genetics and Neurodevelopmental Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.82