The synergistic antitumor effects of psoralidin and cisplatin in gastric cancer by inducing ACSL4-mediated ferroptosis
The combination of PSO and DDP has synergistic antitumor effects on GC cells by inducing ACSL4-mediated ferroptosis. PSO may serve as a nontoxic adjuvant to enhance DDP's efficacy and reduce side effects in GC.
Authors
- Lihong Gan
- Peng Fei Liu (ORCID: https://orcid.org/0000-0003-0411-0488)
- Yaqin Huang (ORCID: https://orcid.org/0000-0002-6016-8687)
- Jinhua Yan (ORCID: https://orcid.org/0000-0001-6246-5266)
- Zheng Li (ORCID: https://orcid.org/0000-0002-2978-2531)
- Ling Yao (ORCID: https://orcid.org/0009-0005-5898-6807)
- Lei Ling (ORCID: https://orcid.org/0000-0002-5051-9797)
Institutions
- Nanchang University (CN)
- Third Affiliated Hospital of Nanchang University (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1186/s41065-025-00591-5
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52