Therapeutic Properties of Nigella sativa (Black Cumin Seeds): A Review

Plants are enriching with many bioactive and nutritional products that are useful for balancing nutrition levels in humans. Many food items have beneficial effects for mankind. From many hundreds of years, herbs are involved in therapeutic activities. Few of food stuff efficiently involve in human’s use such as dates, figs, black cumin seeds (Nigella sativa), olive oil, grapes and other cumin seeds. N. sativa has much importance in diseases curing. Nigella sativa has contained carbohydrates, fats proteins and crude fibre and also have limonene citronelloland carvonein little amounts. Nigella sativa seeds also compose on α-hederin. As cumin seeds have widely used in food stuff for better aroma and traditionally used as medicines against various diseases such as severe dyspepsia, diarrhoea, acute gastritis, cancer and a diabetes. It belongs to the powerful healing family. N. sativa involved in indigestion as stimulator. It stimulates various digestive enzymes which examined in animals (rat pancreas and intestinal mucosa). The Nigella dietary cumin has increased efficiently stimulatory effect on bile flow up to 25%. It increases bile secretions of bile acid in gastrointestinal track. N. sativa has an efficient effect in a diabetic patient. As it lowers the sugar level in diabetic patients and moderate its level. Few years ago, it had been reported that black seeds have an antidiabetic effect in diabetic humans. N. sativa has identified as an anti-inflammatory and analgesic effects by reducing NF-kB. Oil of N. sativa consists of 37.3% p-cymene and 13.7% TQ involve in palliative or inflammatory effect. N. sativa has been broadly studied in vitro and in vivo models differentially about its anti cancer property. N. sativa has an antioxidant and cytotoxic ability with also many other beneficial properties like pro-apoptotic, anti-mutagenic, anti-metastatic and antiproliferative effects in various types of most important cancer cells and lines of cancer cell. In present studies, few therapeutic properties have discussed.