Mendelian randomisation reveals modifiable pathways and epigenetic markers from childhood maltreatment to neuropsychiatric disorders
These results emphasise the need for preventative strategies to reduce childhood maltreatment prevalence, including strengthening support for high-risk families and responsive strategies to mitigate consequences for victims, with clinical screening for childhood maltreatment history and holistic approaches addressing addiction-related, cognitive and socioeconomic mediators.
Authors
- Nicole Ying Ting Ng (ORCID: https://orcid.org/0009-0009-3763-5417)
- Brian Hon‐Yin Chung (ORCID: https://orcid.org/0000-0002-7044-5916)
- Christopher Chun Yu Mak (ORCID: https://orcid.org/0000-0001-6934-6518)
- Jie Zhao (ORCID: https://orcid.org/0000-0002-1564-0057)
- Jennifer Tang (ORCID: https://orcid.org/0000-0002-4160-1713)
Institutions
- Chinese University of Hong Kong (HK)
- University of Hong Kong (HK)
Publication Details
- Journal
- The British Journal of Psychiatry
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1192/bjp.2025.10433
- Primary Topic
- Child Abuse and Trauma
- Type
- article
- Field-Weighted Citation Impact
- 0.00