Gloriosa superba Poisoning-induced Anagen Effluvium
Anagen effluvium, the sudden onset of massive hair loss, usually occurs a few days to weeks after an insult like chemotherapy, radiotherapy, toxin exposure, and alopecia areata. Poisonous plant-induced anagen effluvium is a rare clinical presentation. <i>Gloriosa superba</i> is a creeper that abundantly grows in tropical countries such as Africa and South Asia. It is a cash crop with high colchicine content in all its parts. Accidental or deliberate consumption of <i>G. superba</i> tubers is common in tropical countries due to its easy availability. Within hours after consumption, vomiting, abdominal pain, diarrhea occur followed by bone marrow suppression and multi-organ failure in case of severe poisoning. After weeks of these acute manifestations, most of the patients experience excessive hair loss due to dystrophic anagen effluvium. The management of <i>G. superba</i> poisoning is symptomatic. The hair regrowth is usually spontaneous and complete. We report a case of accidental poisoning of <i>G. superba</i> tubers in a 38-year-old female presenting to a dermatologist with anagen effluvium.
Authors
- Arun Somasundaram (ORCID: https://orcid.org/0000-0001-9796-5471)
- Vinupriya Sakkaravarthi (ORCID: https://orcid.org/0009-0005-9088-0295)
- Sowmya S Aithal
Institutions
- PSG Institute of Medical Sciences & Research (IN)
- SRM Dental College (IN)
- Jawaharlal Institute of Post Graduate Medical Education and Research (IN)
Publication Details
- Journal
- International Journal of Trichology
- Published
- 2025-03-01
- DOI
- https://doi.org/10.4103/ijt.ijt_41_24
- Primary Topic
- Hair Growth and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00