Association of zinc deficiency and risk of new-onset dementia: a retrospective cohort study
Zinc deficiency represents an independent, modifiable risk factor for new-onset dementia with a clear dose-response relationship. These findings support the consideration of zinc status assessment and optimization in dementia prevention strategies. Future randomized controlled trials are warranted to establish causality and determine optimal intervention protocols.
Authors
- I‐Wen Chen (ORCID: https://orcid.org/0009-0004-7122-6901)
- Sheng-Han Huang
- Chun‐Ning Ho (ORCID: https://orcid.org/0000-0001-6469-226X)
- Jheng‐Yan Wu (ORCID: https://orcid.org/0000-0002-3290-1909)
- Yi‐Chen Lai (ORCID: https://orcid.org/0000-0002-9450-5506)
- Kuo-Chuan Hung (ORCID: https://orcid.org/0000-0002-4507-8085)
- W. S. Tsai (ORCID: https://orcid.org/0000-0002-7662-9329)
- Hsiu-Lan Weng
Institutions
- E-Da Hospital (TW)
- Chi Mei Medical Center (TW)
- I-Shou University (TW)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-11-04
- DOI
- https://doi.org/10.3389/fnut.2025.1666887
- Citations
- 1
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 1.12