Febrile rash, shock, and hyperferritinaemia in a young woman: navigating the diagnostic overlap of hemophagocytic lymphohistiocytosis, toxic shock, and viral exanthema

Hyperferritinaemia is a useful biomarker but highly non-specific and must be interpreted within the broader clinical context.Serial trends in inflammatory markers and use of scoring tools such as the HScore guide safe decision-making in suspected hemophagocytic lymphohistiocytosis.Early multidisciplinary review helps prevent unnecessary immunosuppression and ensures timely supportive care.

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Publication Details

Journal
European Journal of Case Reports in Internal Medicine
Published
2025-11-04
DOI
https://doi.org/10.12890/2025_005887
Primary Topic
Autoimmune and Inflammatory Disorders Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Febrile rash, shock, and hyperferritinaemia in a young woman: navigating the diagnostic overlap of hemophagocytic lymphohistiocytosis, toxic shock, and viral exanthema

Pavankumar Hulikere Srinivasaiah, Kasi Vishwanath Surabhi
European Journal of Case Reports in Internal Medicine
Autoimmune and Inflammatory Disorders Research
article

Febrile rash, shock, and hyperferritinaemia in a young woman: navigating the diagnostic overlap of hemophagocytic lymphohistiocytosis, toxic shock, and viral exanthema

Pavankumar Hulikere Srinivasaiah, Kasi Vishwanath Surabhi
article en

Abstract

Hyperferritinaemia is a useful biomarker but highly non-specific and must be interpreted within the broader clinical context.Serial trends in inflammatory markers and use of scoring tools such as the HScore guide safe decision-making in suspected hemophagocytic lymphohistiocytosis.Early multidisciplinary review helps prevent unnecessary immunosuppression and ensures timely supportive care.

European Journal of Case Reports in Internal MedicineVol. 12(12)
University Hospitals Bristol NHS Foundation Trust (GB), At Bristol (GB), Gloucestershire Hospitals NHS Foundation Trust (GB)
Openalex Percentile: Top 57%
Autoimmune and Inflammatory Disorders Research
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