MicroRNA-597-3p targets MACC1 to suppress proliferation and invasion of human ovarian cancer cells
MiR-597-3p functions as a tumor suppressor in ovarian cancer by directly targeting MACC1, thereby inhibiting proliferation, invasion, and survival. These findings highlight the miR-597-3p/MACC1 axis as a potential therapeutic target and suggest miR-597-3p as a promising biomarker for ovarian cancer.
Authors
- Abdulaziz M. Alqahtani (ORCID: https://orcid.org/0009-0004-5753-7199)
- Mohammed Merae Alshahrani (ORCID: https://orcid.org/0000-0002-9387-5492)
- Ahmed Abdullah Al Awadh (ORCID: https://orcid.org/0000-0001-5860-530X)
- Fahad Alshahrani
Institutions
- University of Bisha (SA)
- Najran University (SA)
Publication Details
- Journal
- PeerJ
- Published
- 2025-11-04
- DOI
- https://doi.org/10.7717/peerj.20316
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Najran University