Cellular contributions to the pathogenesis of anti-platelet factor 4 disorders
A deeper understanding of these intercellular pathways will shed light on the role of innate immune cells, in addition to platelets, in creating variable clinical outcomes between anti-PF4 disorders and reveal novel therapeutic targets. This expands our understanding of unifying mechanisms between these disorders and informs future strategies to improve diagnosis and treatment.
Authors
- Ishac Nazy (ORCID: https://orcid.org/0000-0002-5695-4343)
- Jared Treverton (ORCID: https://orcid.org/0009-0000-6416-2453)
- Mark Lychacz
Institutions
- Institute for Transfusion Medicine (US)
- McMaster University (CA)
Publication Details
- Journal
- Current Opinion in Hematology
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1097/moh.0000000000000900
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00