Qing-Re-Xiao-Zheng-yi-qi formula protects renal function by stabilizing lysosomal membranes and inhibiting NLRP3-inflammasome-mediated pyroptosis in diabetic kidney disease
QRXZYQF inhibits NLRP3-mediated podocyte pyroptosis by stabilizing lysosomal membranes, providing insights into its protective mechanism and potential therapeutic targets for DKD.
Authors
- Weijing Liu (ORCID: https://orcid.org/0000-0003-0593-5983)
- Wenjing Zhao
- L Wang
- Yutong Wang (ORCID: https://orcid.org/0000-0002-5819-3787)
- Lei Tian (ORCID: https://orcid.org/0000-0002-7216-5352)
- Yaoxian Wang (ORCID: https://orcid.org/0000-0002-3658-8200)
Institutions
- Capital Medical University (CN)
- Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine (CN)
- Beijing Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-11-03
- DOI
- https://doi.org/10.1080/07853890.2025.2581157
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00