Quantifying the optimal factor VIII levels to achieve patient-centric and clinician-relevant outcomes among people with hemophilia A: a SHELF elicitation study
Standard prophylaxis regimens may not provide sufficient protection for all patients, particularly those with joint damage. A personalized treatment approach, targeting higher FLs when necessary, may be critical for optimizing outcomes.
Authors
- Claudia Mighiu (ORCID: https://orcid.org/0000-0002-2938-4939)
- Maria Elisa Mancuso (ORCID: https://orcid.org/0000-0002-7113-4028)
- Paul McLaughlin (ORCID: https://orcid.org/0000-0002-5962-7647)
- Tom Blenkiron (ORCID: https://orcid.org/0000-0002-5716-0748)
- Tom Burke (ORCID: https://orcid.org/0000-0001-6768-1670)
- Kate Khair (ORCID: https://orcid.org/0000-0003-2001-5958)
- Brian O’Mahony (ORCID: https://orcid.org/0000-0001-9780-6972)
Institutions
- Humanitas University (IT)
- University of Chester (GB)
- Royal Free London NHS Foundation Trust (GB)
- Irish Cancer Society (IE)
- Canadian Hemophilia Society (CA)
- Cheshire West and Chester (GB)
- Haemonetics (United States) (US)
- Indiana Hemophilia and Thrombosis Center (US)
- IRCCS Humanitas Research Hospital (IT)
Publication Details
- Journal
- Expert Review of Hematology
- Published
- 2025-11-04
- DOI
- https://doi.org/10.1080/17474086.2025.2574715
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00