Evaluation of five liquid culture media for rapid detection of Mycobacterium tuberculosis
Carrot- and potato-supplemented Sauton medium demonstrated comparable performance to the MGIT 960 system for specimens with medium-to-high bacterial loads. Carrot extract, oleic acid, and choline chloride significantly enhanced the detection rate of low-inoculum, with carrot extract exhibiting the most pronounced growth-promoting effects. This study validates an accessible alternative to expensive imported media, particularly beneficial for resource-limited settings.
Authors
- Yihui Xie (ORCID: https://orcid.org/0000-0001-8415-9147)
- Yinzhong Shen (ORCID: https://orcid.org/0000-0002-7604-5139)
- Zhiqiang Zhao (ORCID: https://orcid.org/0000-0002-2081-3581)
- Yuxin Shi (ORCID: https://orcid.org/0000-0001-8051-448X)
- Zhaoqin Zhu (ORCID: https://orcid.org/0000-0003-1101-5999)
- Xueqin Qian (ORCID: https://orcid.org/0000-0002-7066-9581)
Institutions
- Fudan University (CN)
- Shanghai Public Health Clinical Center (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-11-04
- DOI
- https://doi.org/10.3389/fcimb.2025.1655595
- Citations
- 1
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- Science and Technology Commission of Shanghai Municipality
- Shanghai Hospital Development Center